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Protein Folding De novo Protein Design
Ranjit Ranbhor Soumendra Rana Anil Kumar Deepa Pednekar Kirti Patel Abhijit Tendulkar Sourav Das
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Protein Design in L and D - Amino Acid Structures as the Alphabet. Durani, S. Accounts
Electrostatics-defying interaction between arginine termini as a thermodynamic driving force
Analysis of Structural Consensus of the Zinc Coordination Centers of Metalloprotein Structures.
A mixed- miniprotein stereochemically reprogrammed to high-binding affinity for acetylcholine.
A double catgrip mixed and mini protein only 20 residues long. Rana, S.; Kundu, B.; Durani,S.
The interplay of sequence and stereochemistry in defining conformation in proteins and
The link between sequence and conformation in protein structures appears to be stereochemically
Computational design of proteins stereochemically optimized in size, stability and folding
A Small Peptide
Stereochemically Customized as a Globular Fold with a Molecular
Cleft.
Simulated Folding of Polypeptides of Diversified Molecular
Tacticity. Implication for Protein
Stereospecific Peptide Folds. A Rationally Designed Molecular Bracelet. Rana, S.; Kundu, B.; Durani, S. Chem. Comm., 2462-2463 (2004).
Existence of specific folds in Polyproline-II ensembles of
an unfolded Alanine Peptide detected
Mechanism-based protein design: Attempted "nucleation-condensation" approach to a possible minimal helix-bundle protein. Mohanraja, K.; Dhanasekaran, M.; Kundu, B.; Durani, S.. Department of Chemistry, Indian Institute of Technology, Bombay, Mumbai, India. Biopolymers, 70(3), 355-363, (2003).
Combined sequence and structure analysis of the fungal laccase family. Kumar, S. V. Suresh; Phale, Prashant S.; Durani, S.; Wangikar, Pramod P. Biotechnology and Bioengineering, 83(4), 386-394, (2003).
Solution conformation of a rationally designed nonapeptide. Dhanasekaran, M.; Srivastava, Sudha; Raju, E. B.; Durani, S. Physiological Chemistry and Physics and Medical NMR , 33(2), 163-174, (2001).
Conformational effects of C-dipropargylglycine as a constrained residue. Damodharan, L.; Mohanraja, K.; Kotha, S.; Durani, S.; Pattabhi, V. Biopolymers 59(5), 330-338, (2001).
Modification of constrained peptides by ring-closing metathesis reaction. Kotha, S.; Sreenivasachary, N.; Mohanraja, K.; Durani, S. Bioorganic & Medicinal Chemistry Letters 11(11), 1421-1423, (2001).
Conformational preferences of heterochiral peptides. Crystal structures of heterochiral peptides Boc-(D) Val-(D) Ala-Leu-Ala-OMe and Boc-Val-Ala-Leu-(D) Ala-OMe- enhanced stability of sheet through C-H...O hydrogen bonds. Fabiola, G. Felcy; Bobde, Vivek; Damodharan, L.; Pattabhil, Vasantha; Durani, S. Journal of Biomolecular Structure & Dynamics , 18(4), 579-594, (2001).
N-1 and N-2 positional effects in the propagation of 310-type fold in the helical model peptide Boc-(D)Glu-Pro-Ala-Lys-Ala-Leu-Ala-OMe. Beri, S.; Srivastava, Sudha; Dhanasekaran, M.; Phadke, Ratna S.; Durani, S. Magnetic Resonance in Chemistry 38(4), 257-264, (2000).
A Rationally Designed Turn-Helix Peptide. Dhanasekaran, M.; Fabiola, F.; Pattabhi, V.; Durani, S. Journal of the American Chemical Society , 121(23), 5575-5576, (1999).
Charge and solvation effects in anion recognition centers: an inquiry exploiting reactive arginines. Jairajpuri M A; Azam N; Baburaj K; Bulliraju E; Durani S. Biochemistry, 37(30), 10780-91, (1998).
Reengineering a type II turn as a potential helix nucleator. Part I. Crystal structure of Boc-Val-Pro-(D)Asp-Asp-Val-OMe monohydrate. Fabiola, G. Felcy; Pattabhi, Vasantha; Raju, E. B.; Durani, S. Journal of Peptide Research , 50(5), 352-356, (1997)
Configurationally guided peptide conformational motifs: crystal structure of a L D L D D L type hexapeptide fold. Fabiola, F.; Pattabhi, V.; Rawale, S.; Raju, E. B.; Durani, S. Chemical Communications (Cambridge) (15), 1379-1380, (1997).
Crystal structures of heterochiral peptides. Part II. tert-Boc-valyl-D-alanyl-leucyl-alanyl methoxide. Nagarajan, V.; Pattabhi, Vasantha; Johnson, A.; Bobde, V.; Durani, S. Journal of Peptide Research 49(1), 74-79, (1997).
Crystal structure of a D-residue containing tetrapeptide. 1. tert-Boc-D-valyl-alanyl-leucyl-alanyl methoxide, butanol solvate. Bobde, V.; Durani, S.; Pattabhi, Vasantha; Sadasivan, C. Dep. Chem., Univ. Madras, Madras, India. International Journal of Peptide & Protein Research 45(4), 332-6, (1995).
A single point chiral inversion that self organizes a random coil peptide. Apolar solvent conformation of Boc-(L/D)-Glu-Ala-Leu-LysNHMe. Bobde, V.; Beri, S.; Rawale, S.; Satyanarayana, C. V. V.; Durani, S.. Biotechnol. Cent., Indian Inst. Technol., Bombay, India. Tetrahedron 51(10), 3077-86, (1995).
Harnessing D-amino acids for peptide motif designs. Synthesis and solution conformation of Boc-D-Glu-Ala-Gly-Lys-NHMe and Boc-L-Glu-Ala-Gly-Lys-NHMe. Bobde V; Sasidhar Y U; Durani S International journal of peptide and protein research 43(3), 209-18, (1994).
HOCGO and DMACGO. Two coumarin derived alpha-dicarbonyls suitable as pH and polarity sensitive fluorescent reporters for proteins that can be targeted at reactive arginines. Baburaj K; Azam N; Udgaonkar D; Durani S. Biochimica et biophysica acta 1199(3), 253-65, (1994).
Metastable ion decomposition and collisional activation mass spectra of 1,2,3-triarylpropen-1-ones. Madhusudanan, K. P.; Durani, S.; Reddy, D. M.; Kapil, R. S.; Itagaki, Y.; Nojima, K. Organic Mass Spectrometry 26(4), 298-304, (1991).
Exploring borate-activated electron-rich glyoxals as the arginine-reactivity probes. The reactivities of functionally critical arginines in some representative enzymes. Baburaj K; Saeed A; Azam N; Durani S Biochimica et biophysica acta 1078(2), 258-64., (1991).
Structure-activity relationship of antiestrogens. Phenolic analogues of 2,3-diaryl-2H-1-benzopyrans. Sharma A P; Saeed A; Durani S; Kapil R S Medicinal Chemistry Division, Central Drug Research Institute, Lucknow, India Journal of medicinal chemistry 33(12), 3222-9, (1990).
Structure-activity relationship of antiestrogens. Effect of the side chain and its position on the activity of 2,3-diaryl-2H-1-benzopyrans. Sharma A P; Saeed A; Durani S; Kapil R S Journal of medicinal chemistry , 33(12), 3216-22, (1990).
Structure-activity relationship of antiestrogens. Studies on 2,3-diaryl-1-benzopyrans. Saeed A; Sharma A P; Durani N; Jain R; Durani S; Kapil R S. Journal of medicinal chemistry 33(12), 3210-6, (1990).
Occurrence of bends in bradykinin dissolved in DMSO-d6. Mirmira, Suman R.; Durani, S.; Srivastava, Sudha; Phadke, Ratna S. Magnetic Resonance in Chemistry 28(7), 587-93, (1990)
Collisional activation spectra of the adduct ions of 1,2,3-triarylpropenones under ammonia chemical ionization conditions. Madhusudanan, K. P.; Durani, S.; Kapil, R. S.; Fraisse, D. Organic Mass Spectrometry 25(5), 265-70, (1990).
Structure-activity relationship of antiestrogens: a study using triarylbutenone, benzofuran, and triarylfuran analogues as models for triarylethylenes and triarylpropenones. Durani N; Jain R; Saeed A; Dikshit D K; Durani S; Kapil R S. Journal of medicinal chemistry 32(8), 1700-7, (1989).
Reduction reaction in triarylpropenones under chemical ionization conditions. Madhusudanan, K. P.; Jain, Raka; Durani, S.; Kapil, R. S. Cent. Drug Res. Inst., Lucknow, India. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry 28B(12), 1082-4, (1989).
Structure-activity relationship of estrogens: receptor affinity and estrogen antagonist activity of certain (E)- and (Z)-1,2,3-triaryl-2-propen-1-ones. Mittal S; Durani S; Kapil R S Journal of medicinal chemistry 28(4), 492-7, (1985).
Fragmentation and rearrangement reactions in certain 1,2,3-triaryl-2-propen-1-ones following electron impact and chemical ionization. Madhusudanan, K. P.; Mittal, Shubhra; Durani, S.; Kapil, R. S. Oganic Mass Spectrometry 20(3), 215-22, (1985).
Cis isomer of centchroman--a selective ligand for the microsomal antiestrogen binding site. Saeed A; Durani N; Durani S; Ray S; Kapil R S Biochemical and biophysical research communications, 125(1), 346-52, (1984).
Antifertility agents. 38. Effect of the side chain and its position on the activity of 3,4-diarylchromans. Salman, M.; Ray, Suprabhat; Agarwal, A. K.; Durani, S.; Setty, B. S.; Kamboj, V. P.; Anand, N. Journal of Medicinal Chemistry 26(4), 592-5, (1983).
Structure-activity relationship of estrogens: a study involving cyclofenil as the model compound. Garg, Shubhra; Bindal, R. D.; Durani, S.; Kapil, R. S. Journal of Steroid Biochemistry 18(1), 89-95, (1983).
Utility of 4-trimethylsiloxyphenylmagnesium bromide in Grignard reactions. Bindal, Rajeshwar D.; Durani, S.; Kapil, Randhir S.; Anand, Nitya. Synthesis (5), 405-7, (1982).
A possible basis for structure-function relationship of estrogens. Durani, S.; Anand, Nitya. Cent. Drug Res. Inst., Lucknow, India. International Journal of Quantum Chemistry 20(1), 71-83, (1981).
An improved procedure for isolation of rat fetoprotein. Ali, Masarrat; Balapure, Anil K.; Durani, S.; Sahib, Maharaj K. Div. Biochem., Cent. Drug Res. Inst., Lucknow, India. Indian Journal of Biochemistry & Biophysics , 18(2), 105-9, (1981).
Studies in antifertility agents. Part XVIII. 2 ,6 -Diethyl-3-(p-hydroxyphenyl)-trans-bicyclo[4.3.0]nonan-7 -ol and 6 -methyl-3-(p-hydroxyphenyl)-2 - propyl-trans-bicyclo[4.3.0]nonan-7 -ol. Gupta, R. C.; Durani, S.; Agarwal, A. K.; Kamboj, V. P.; Anand, Nitya. Organic Chemistry Including Medicinal Chemistry, 19B(10), 886-90, (1980).
Seco-estradiols and some non-steroidal estrogens: structural correlates of estrogenic action. Durani, S.; Agarwal, A. K.; Saxena, R.; Setty, B. S.; Gupta, R. C.; Kole, P. L.; Ray, S.; Anand, Nitya. Journal of Steroid Biochemistry , 11(1A), 67-77, (1979).
6,11-Dimethoxycarbonyl-5,6,7,8,9,10,11,12-octahydrobenzocyclodecene. Convenient synthesis of disubstituted cycloalkanes. Durani, S.; Kapil, R. S.; Anand, Nitya. Indian Journal of Chemistry 13(9), 946-7, (1975).
Structure-activity relationship of estrogens: a study involving cyclofenyl as the model compound. Garg S; Bindal R D; Durani S; Kapil R S Journal of steroid biochemistry , 18(1), 89-95, (1983).
Antifertility agents. 38. Effect of the side chain and its position on the activity of 3,4-diarylchromans. Salman M; Ray S; Agarwal A K; Durani S; Setty B S; Kamboj V P; Anand N Journal of medicinal chemistry , 26(4), 592-5, (1983)
Dose dependent modulation of receptor dynamics and uterine growth in immature rat by estradiol: importance of an additional nuclear binding at 24 hr for long-term (72 hr) uterine growth. Agarwal A K; Durani S; Setty B S Endokrinologie , 79(2), 235-41, (1982).
An improved procedure for isolation of rat alpha-fetoprotein. Ali M; Balapure A K; Durani S; Sahib M K Indian journal of biochemistry & biophysics 18(2), 105-9, (1981).
Seco-oestradiols and some non-steroidal oestrogens: structural correlates of oestrogenic action. Durani S; Agarwal A K; Saxena R; Setty B S; Gupta R C; Kole P L; Ray S; Anand N Journal of steroid biochemistry 11(1A), 67-77, (1979).
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