Glycochemistry Research Lab

Department of Chemistry
Indian Institute of Technology Bombay
Powai, Mumbai 400076

Phone : 022-2576 7166
Fax      : 022 -2576 7152
Email   : suvarn[at]chem.iitb.ac.in

Publications:

Year Index :

2021  |  2020  |  2019  |  2018  | 2017  | 2016  | 2015  | 2014  | 2013  | 2012  | 2011  | 20102009  | 2008  | 2007  | 2006  | 2005  |  2004  | 2003  


Total number of publications = 78, citations = 2282, h index = 24, i10 index = 43



2021

63. Total Synthesis and Structure Revision of a Fungal Glycolipid Fusaroside.
 
Jana, S. Sarpe, V. A. Kulkarni S. S. Org. Lett., 2021,23, 1664-1668. DOI .


2020

62. Synthesis of Nonulosonic Acid
 
Pradhan. K.; Kulkarni, S. S. Eur. J. Org. Chem., 2020,6819-6830. DOI .


61. Recent advances in β-L-rhamnosylation
 
Rai, D.; Kulkarni, S. S. Org. Biomol. Chem., 2020, 18, 3216-3228. DOI .


60. Metabolic inhibitors of bacterial glycan biosynthesis
 
D. A. Williams, K. Pradhan, A. Paul, I. R. Olin, O. T. Tuck, K. D. Moulton, S. S. Kulkarni and D. H. Dube Chem. Sci., 2020, 11, 1761-1774. DOI .


2019

59. Novel Protecting Groups for Oligosaccharides Synthesis
 
Bhaswati Ghosh and Suvarn S. Kulkarni Chemistry An Asian Journal, 2019, DOI .


58. Total Synthesis of the Lipid-Anchor-Attached Core Trisaccharides of Lipoteichoic Acids of Streptococcus pneumoniae and Streptococcus oralis Uo5
 
Balasaheb K. Ghotekar, Ananda Rao Podilapu and Suvarn S. Kulkarni Org. Lett. 2019, DOI .


57. Total Syntheses of Conjugation-ready Trisaccharide Repeating Units of Pseudomonas aeruginosa O11 and Staphylococcus aureus Type 5 Capsular Polysaccharide for Vaccine Development
 
Archanamayee Behera,† Diksha Rai,† and Suvarn S. Kulkarni J. Am. Chem. Soc. 2019, DOI .


2018

56. Synthesis of Rare Deoxy Amino Sugar Building Blocks Enabled the Total Synthesis of a Polysaccharide Repeating Unit Analogue from the LPS of Psychrobacter cryohalolentis K5T
 
Emmadi, M.; Kulkarni, S. S. J.Org. Chem. 2018, 83, 14323-14337.


55. Total Synthesis of Emmyguyacins A and B, Potential Fusion Inhibitors of Influenza Virus
 
Jana, S.; Sarpe, V.A.; Kulkarni, S. S. Org. Lett. 2018,20, 6938-6942.


54. Chemical Synthesis of Rare, Deoxy-Amino Sugars Containing Bacterial Glycoconjugates as Potential Vaccine Candidates
 
Behera, A.; Rai, D.; Kushwaha, D.; Kulkarni, S. S. Org. Lett. 2018, 20 , 5956-5959.


53. Chemical Synthesis of Rare, Deoxy-Amino Sugars Containing Bacterial Glycoconjugates as Potential Vaccine Candidates
 
Behera, A.; Kulkarni, S. S. Molecules 2018, 23, 1997.


52. Expeditious Synthesis of Ieodoglucomides A and B from the Marine-Derived Bacterium Bacillus Licheniformis
 
Podilapu, A. R.; Emmadi, M.; Kulkarni, S. S. Eur.J.Org.Chem. 2018, 3230-3235.


51. Correction to "One-Pot"Protection, Glycosylation, and Protection-Glycosylation Strategies of Carbohydrates
 
Kulkarni, S. S.; Wang, C.; Sabbavarapu, N. M.; Podilapu, A. R.; Liao, P.; Hung, S. Chem. Rev. 2018, 118, 8025-8104.


2017

50. Total Synthesis of Repeating Unit of O-Polysaccharide of Providencia alcalifaciens O22 via One-pot Glycosylation
 
Podilapu, A. R.; Kulkarni,S.S. Org. Lett. 2017, 19, 5466-5469


49. Assembling Glycan-Charged Dolichol Phosphates: Chemoenzymatic Synthesis of a Haloferax volcanii N-Glycosylation Pathway Intermediate
 
Elharar, Y.; Podilapu, A. R.; Guan, Z.; Kulkarni, S. S.; Eichler, J Bioconjugate Chem. 2017, Just Accepted.
DOI :

48. Chemical Synthesis of Biosurfactant Succinoyl Trehalose Lipids
 
Jana, S.; Mondal, S.; Kulkarni, S. S. Org. Lett. 2017, 19, 1784-1787.
DOI :

2016

47. Development of Rare Bacterial Monosaccharide Analogs for Metabolic Glycan Labeling in Pathogenic Bacteria
 
Clark, E. L.; Emmadi, M.; Krupp, K. L.; Podilapu, A. R.; Helble, J. D.; Kulkarni, S. S.; Dube, D. H. ACS Chem. Biol. 2016, 11, 3365-3373.
DOI :

46. From L-Rhamnose to Rare 6-Deoxy-L-Hexoses
 
Sanapala, S. R.; Kulkarni, S. S. Org. Lett. 2016, 18, 3790-3793.
DOI :

45. First Total Synthesis of Trehalose Containing Tetrasaccharides from Mycobacterium smegmatis
 
Chaube, M. A.; Sarpe, V.A.; Jana, S.; Kulkarni, S. S. Org. Biomol. Chem. 2016, 14, 5595-5598.
DOI :

44. Expedient Route to Access Rare Deoxy Amino L-Sugar Building Blocks for the Assembly of Bacterial Glycoconjugates
 
Sanapala, S. R.; Kulkarni, S. S. J. Am. Chem. Soc. 2016, 138, 4938-4947.
DOI :

43. Synthesis of Mycobacterium tuberculosis Sulfolipid-3 Analogues and Total Synthesis of the Tetraacylated Trehaloglycolipid of Mycobacterium paraffinicum
 
Sarpe, V.A.; Jana, S.; Kulkarni, S. S., Org. Lett. , 2016, 18, 76-79.
DOI :

2015

42. First Total Synthesis of Trehalose Containing Branched Oligosaccharide OSE-1 of Mycobacterium gordonae (Strain 990)
 
Chaube, M. A.; Kulkarni, S. S. Chem. Eur. J., 2015, 21, 13544-13548.
DOI :

41. One-pot Synthesis of Bicyclic Sugar Oxazolidinone from D-Glucosamine
 
Sanapala, S. R.; Kulkarni, S. S.; RSC Adv. 5, 22426-22430, 2015 .
DOI :

40. First Synthesis of the α-L-Serine Linked Consensus Disaccharide of Neisseria gonorrhoeae and Neisseria meningitides
 
Jana, S., Emmadi, M., Kulkarni, S. S., Isr. J. Chem. 55, 398-402.
DOI :

2014

39. Total Synthesis of MECA-79
 
Behera, A.; Emmadi, M.; Kulkarni, S. S., RSC Advances, 2014, 4, 58573-58580.
DOI :

38. Expeditious Synthesis of Mycobacterium tuberculosis Sulfolipids SL‑1 and Ac2SGL Analogues
 
Sarpe, V.A.; Kulkarni, S. S., Org. Lett. 16, 5732-5735,  
DOI :

37. First Synthesis of Bacillus cereus Ch HF-PS Cell Wall Trisaccharide Repeating Unit
 
Podilapu, A. R. ; Kulkarni, S. S.; Org. Lett.,  2014, 4336-4339.
DOI :

36. Total Synthesis of the Bacillosamine Containing alpha-L-Serine Linked Trisaccharide of Neisseiria meningitidis
 
Emmadi, M.; Kulkarni, S. S. Carbohydr. Res., 2014, 399, 57-63,  
DOI :

35. Recent Advances in Synthesis of Bacterial Rare Sugar Building Blocks and Their Applications
 
Emmadi, M.; Kulkarni, S. S., Nat. Prod. Rep., 2014,  
DOI :

34. Chemical Synthesis of Asparagine Linked Archaeal N-Glycan from Methanothermus Fervidus
 
Sanapala, S. R.; Kulkarni, S. S., Chem. Eur. J. 2014,  20, 3578-3583.,  
DOI :

33. Synthesis of the trisaccharide moiety and a cholesteryl analog of phyteumosides
 
Adak, S.; Emmadi, M. and Kulkarni, S. S., RSC Advances, 2014, 4, 7611-7616,  
DOI :

2013

32. Synthesis of a C-Glycoside Analog of beta-Galactosyl Ceramide, a Potential HIV-1 Entry Inhibitor
 
Thota V.N.; Brahmaiah, M. and Kulkarni, S. S.,  J.Org. Chem, 2013, 78, 12082-12089,  
DOI :

31. Regioselective Protection and Functionalisation of Trehalose
 
Sarpe, V.A.; Kulkarni, S. S., Trends In Carbohydrate Research, 2013, 5, 8-33.  
DOI :

30. Desymmetrization of Trehalose via Regioselective Reductive DIBAL Ring Opening of Benzylidene and Substituted Benzylidene Acetals
 
Sarpe, V. A.; Kulkarni, S. S., Org. Biomol. Chem., 2013, 11, 6460-6465,  
DOI :

29. Synthesis of Orthogonally Protected Bacterial, Rare Sugar and D-Glycosamine Building Blocks
 
Emmadi, M.; Kulkarni, S. S. Nature Protocols 2013. 8, 1870 - 1889,  
DOI :

28. Orthogonally Protected D-Galactosamine Thioglycoside Building Blocks via Highly Regioselective, Double Serial and Double Parallel Inversions of β-Thiomannoside
 
Emmadi, M.; Kulkarni, S. S. Org. Biomol. Chem., 2013, 11, 4825-4830,  
DOI :

27. Expeditious synthesis of bacterial, rare sugar building blocks to access the prokaryotic glycome
 
Emmadi, M.; Kulkarni, S. S. Org. Biomol. Chem., 2013, 11,3098-3102. (Top 10 accessed articles),
DOI :

26. Concise synthesis of alpha-galactosyl ceramide from D-galactosyl iodide and D-lyxose
 
Yu-Fen Yen, Suvarn S. Kulkarni, Chun-Wei Chang, Shun-Yuan Luo, Carbohydr. Res. 2013, 368, 35-39,  
DOI :




2012

25. Synthesis of β-C-galactosyl D- and L-alanines
 
Thota, V. N.; Gervay-Hague, J.; Kulkarni, S. S. Org. Biomol. Chem., 2012, 10, 8132 - 8139,  
DOI :

24. Stereoselective Construction of 1,1-alpha,alpha-Glycosidic Bonds
 
Chaube, M. A.; Kulkarni, S. S. Trends in Carbohydr. Res. 2012 , 4, 1-19.
 DOI :



2011

23. Synthesis of Maradolipid
 
Sarpe, V. A.; Kulkarni, S. S. J. Org. Chem. 2011,76, 6866-6870,  
DOI :

22. Development of Sodium-Dependent Glucose Co-Transporter 2 Inhibitors as Potential Anti-Diabetic Therapeutics
 
Ho, L.-T.; Kulkarni, S. S.; Lee, J.-C. Curr. Top. Med. Chem. 2011, 11, 1476-1512,  
DOI :

21. Rapid Transformation of D-Mannose into Orthogonally Protected D-Glucosamine and D-Galactosamine Thioglycosides
 
Emmadi, M.; Kulkarni, S. S. J. Org. Chem. 2011, 76, 4703-4709,  
DOI :



2010

20. One-Pot Syntheses of Immunostimulatory Glycolipids Schombs, M.; Park, F. E.; Du, W.; Kulkarni S. S.; Gervay-Hague, J , J. Org. Chem. Featured Article, 2010, 75, 4891-4898



2009

19. "Synthesis of Alginate Oligosaccharides Containing L-guluronic acids" Chi, F.-C.; Kulkarni, S. S.; Medel Manuel L. Z.; Hung, S.-C. Chem. Asia. J. 2009, 4, 386-390

18. "Two-step Synthesis of the Immunogenic Bacterial Glycolipid BbGL1". Kulkarni S. S ; Gervay-Hague, J. Org. Lett. 2008, 10, 4739-4742



2008

17. "Regioselective One Pot Protection of Glucose" Wang, C.-C.; Kulkarni, S. S.; Lee J.-C.; Luo, S.-Y.; Hung S.-C. Nature Protocols 2008, 3, 97-113



2007

16. "Regioselective and One Pot Protection of Carbohydrates" Wang, C.-C.; Lee J.-C.; Luo, S.-Y.; Kulkarni, S. S.; Huang, Y.-W.; Lee, C.-C.; Chang, K.-L.; Hung S.-C. Nature 2007, 446, 896-899

15. "Efficient, One-Pot Syntheses of Biologically Active alpha-linked Glycolipids" Du, W.; Kulkarni, S. S.; Gervay-Hague, J. Chem Commun 2007, 2336-2338



2006

14. "Efficient Synthesis of a C-Analog of the Immunogenic Bacterial Glycolipid BbGL2". Kulkarni S. S ; Gervay-Hague, J. Org. Lett. 2006, 8, 5765-5768

13. "Synthesis of 48 Disaccharide Building Blocks for the Assembly of Heparin and Heparan Sulfate Oligosaccharide Library." Lu, L.-D.; Shie, C.-R.; Kulkarni, S. S.; Pan, G.-R.; Lu, X.-A.; Hung, S.-C. Org. Lett. 2006, 8, 5995-5998

12. "A Concise Synthesis of Tetrahydroxy-LCB, alpha-Galactosyl Ceramide, and 1,4-Dideoxy-1,4-imino-L-ribitol via D-Allosamines as Key Building Blocks" Luo, S.-Y.; Kulkarni, S. S.; Chou, C.-H.; Liao, W.-M.; Hung, S.-C. J. Org. Chem. 2006, 71, 1226-1229

11. "2-Allyloxyphenyl Glycoside as a New and Stable Type of Glycosyl Donors" Lee, J.-C.; Pan, G.-R.; Kulkarni, S. S., Luo, S.-Y; Liao, C.-C.; Hung, S.-C. Tetrahedron Lett. 2006, 47, 1621-1624



2005

10. "Neighboring Group Participation of 9-Anthracenemethyl Group in Glycosylation: Preparation of Unusual C-glycosides", Kulkarni, S. S.; Liu, Y.-H.; Hung, S.-C. J. Org. Chem. 2005, 70, 2808-2811

9. "Metal Trifluoromethanesulfonates as Versatile Catalysts in Carbohydrate Synthesis" Kulkarni, S. S.; Hung, S.-C. Lett. Org. Chem. 2005, 2, 670-677

8. "Cu(OTf)2-catalyzed Regioselective Reductive Ring Opening of Benzylidene Acetals" Shie, C.-R.; Tzeng, Z.-H.; Kulkarni, S. S.; Uang, B.-J.; Hsu, C.-Y.; Hung, S.-C. Angew. Chem. Int. Ed. 2005, 44, 1665-1668



2004

7. "Synthesis of Heparin Oligosaccharides", Lee, J.-C.; Lu, X.-A.; Kulkarni, S. S.; Wen, Y.-S.; Hung, S.-C. J. Am. Chem. Soc. 2004, 126, 476-477

6. "Recent Advances in the Applications of D- and L-1,6-Anhydropyranoses for the Synthesis of Oligosaccharides and Nature Products", Kulkarni, S. S.; Lee, J.-C.; Hung, S.-C. Curr. Org. Chem. 2004, 8, 475-509

5. "Biologically Potent L-Hexoses and 6-Deoxy-L-hexoses: Their Syntheses and Applications", Kulkarni, S. S.; Chi, F.-C.; Hung, S.-C. J. Chin. Chem. Soc. 2004, 51(Special Issue dedicated to Prof. Sunney I. Chan to celebrate his 67th Birthday), 1193-1200

4. "Regioselective Glycosylation of Neamine Core: A Facile Entry to Kanamycin B-Related Analogues", Chou, C.-H; Wu, C.-S.; Chen, C.-H.; Lu, L.-D.; Kulkarni, S. S.; Wong, C.-H.; Hung, S.-C. Org. Lett. 2004, 6, 585-588

3. "From D-Glucose to Biologically Potent L-Hexoses: Synthesis of alpha-L-Iduronidase Fluorogenic Detector and the Disaccharide Moieties of Bleomycin A2 and Heparan Sulfate", Lee, J.-C.; Chang, S.-W.; Chi, F.-C.; Chen, C.-S.; Wen, Y.-S.; Wang, C.-C.; Kulkarni, S. S.; Puranik, R.; Liu, Y.-H.; Hung, S.-C. Chem. Eur. J. 2004, 10, 399-415



2003

2. "Cu(OTf)2-catalyzed Neat Per-O-acetylation of Hexoses with Stoichiometric Amount of Acetic Anhydride and One-Pot Solvent-free Per-O-acetylation-substitution to the Corresponding Thioglycosides", Tai, C.-A.; Kulkarni, S. S.; Hung, S.-C. J. Org. Chem. 2003, 68, 8719-8722

1. "Cu(OTf)2-catalyzed Et3SiH-reductive Etherification of Various Carbonyl Compounds with Trimethylsilyl Ethers", Yang, W.-C.; Lu, X.-A.; Kulkarni, S. S.; Hung, S.-C. Tetrahedron Lett. 2003, 44, 7837-7840

Patents

  1. One pot synthesis of unprotected alpha/beta-O-glycolipids' Gervay-Hague J.; Du, W.; Kulkarni, S. S.; Schombs, M. PCT Int. Appl.(2008), WO 2008124729 A1 20081016

  2. Method for preparing hexose derivatives’ Hung, S.-C.; Wang, C.-C.; Lee, J.-C.; Luo, S.-Y.; Kulkarni, S. S.; Huang, Y. W.; Lee, C. C.; Chang, K. L., PCT Int. Appl. Publication No. US 7985856 B2 published on 26-Jul-2011 Application No. US 11/874697 filed on 18-Oct-2007.

 

Book Chapters :

  1. "Synthesis of Hemagglutinin-Binding Trisaccharides" Wang, C.-C.; Kulkarni , S. S.; Zulueta, M. M. L.; Hung, S.-C. In 'The Molecular Immunology of Complex Carbohydrates-3, Advances in Experimental Medicine and Biology 705, Springer Science+Business Media, LLC, 2011, Chapter 37, pp 691-726.

  2. Glycosyl chlorides, bromides and iodides, Kulkarni, S.S. and Gervay-Hague, J. Handbook of Chemical Glycosylation: Advances in Stereoselectivity and Therapeutic Relevance, Demchenko, A. V. Eds., Wiley-VCH, 2008, pp59-93

  3. Synthesis of glycolipid antigens, Kulkarni, S.S, and Gervay-Hague, J. In Chemical Glycobiology, Eds. Chen, X.; Halcomb, R.; Wang, P. G., ACS Symposium series 2008, 990, pp153-166